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Workshop III:Exploring Protein Complex Systems and Enzymatic Functions through Advanced Structural Biology Approaches from Dynamic and Static Perspectives

Chairs: Chun-Hsiang Huang (黃駿翔) & Yane-Shih Wang (王彥士)

September 4 (Thursday)Place: L100

08:30

Registration -@Activity Center (Entrance 5)

09:00

SIKA十週年 --- ACNS and NSRRC Remote Celebration

Place: D260

Session Chair: Yane-Shih Wang (王彥士)

10:30

III1

GlycoSwitch — A Novel Signaling Circuit to Control Endocytosis

Ludger Johannes, Institut Curie, Paris, France)

11:10

III2

Uncovering the Mechanisms of how Signaling Proteins Assemble in Forward and Reverse Orders by Cryo-EM and X-ray Studies

Su-Chang Lin (林世昌), Academia Sinica (中央研究院)

11:40

III3

Mechanistic Insights into Histone Modification-driven Structural Remodeling of DNMT3B in DNA Methylation

Hanna S. Yuan (袁小琀), Academia Sinica (中央研究院)

12:10

Group Photo & Lunch

Session Chair: Yane-Shih Wang (王彥士)

13:00

III4

Crystallographic Analysis Revealing the Mechanistic Role of the N-terminal Domain of Lon AAA+ Protease

Chung-I Chang (張崇毅), Academia Sinica (中央研究院)

13:30

III5

Structural Insights and Catalytic Mechanisms of Particulate Methane Monooxygenase (pMMO) from Methylococcus capsulatus (Bath) and Alkane Hydroxylase (AlkB) from Pseudomonas putida GPo1

Steve Sheng-Fa Yu (俞聖法), Academia Sinica (中央研究院)

14:00

III6

Synthesis of Chirality-specific Building Units Using Biocatalysts of Structure-/Mechanism-based Engineering

Tsung-Lin Li (李宗璘), Academia Sinica (中央研究院)

14:30

Coffee Break

Session Chair: Chun-Hsiang Huang (黃駿翔)

14:45

III7

Time-resolved Structural Biology – A New Frontier

Ming-Daw Tsai (蔡明道), Academia Sinica (中央研究院)

15:25

III8

Advancements in Macromolecular Crystallography Beamlines at the Swiss Light Source

Meitian Wang, Swiss Light Source (SLS), Switzerland

16:05

III9

From Femtoseconds to Seconds: Applying Different TRX Methodologies to Bridge the Vast Time-spans of Protein Function

Manuel Maestre-Reyna (馬左仲), National Taiwan Univ. (國立臺灣大學)

16:35

III10

The Current Status and Future Plan of Protein Crystallography Beamlines at NSRRC

Chien-Chang Tseng (曾建璋), NSRRC (國家同步輻射研究中心)

17:05

Discussion & Closing Remarks

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